"Examining the link between tooth agenesis and papillary thyroid cancer: is there a risk factor?" Observational study.

ABSTRACT:

Background

Mutations in one or multiple genes can lead to hypodontia and its characteristic features. Numerous studies have shown a strong genetic influence on the occurrence of hypodontia, and identified several genes, including AXIN2, EDA, FGF3, FGFR2, FGFR10, WNT10A, MSX1, and PAX9, that are directly associated with dental agenesis and carcinogenesis. The objective of this study was to investigate the occurrence and pattern of tooth agenesis, microdontia, and palatally displaced canine (PDC) in women diagnosed with papillary thyroid cancer (PTC), compared to a control group of women without any malignancy or thyroid disease.

Materials and methods

This case-control study was carried at the Department of Orthodontics, School of Dental Medicine University of Zagreb, and Depa

SUBMITTER: Matosic Z 

PROVIDER: S-EPMC10961299 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature