Association of Physical Frailty and Cognitive Function in a Population-Based Cross-Sectional Study of American Older Adults.

ABSTRACT:

Introduction

Cognitive impairment and frailty are prevalent in older persons. Physical frailty is associated with cognitive decline; however, the role of effect modifiers such as age, sex, race/ethnicity, and cognitive reserve is not well understood.

Methods

Cross-sectional data from the National Health and Nutrition Examination Survey (2011-2014) were obtained for participants aged ≥60 years. Complete availability of cognitive scores was an inclusion criterion. Physical frailty was defined by the presence of exhaustion, weakness, low body mass, and/or low physical activity, and categorized into three groups: robust (0 present), pre-frail (1-2 present), or frail (3-4 present). Four cognitive test scores were converted to z-scores, and global cognition (composite z-score) was

SUBMITTER: Karanth S 

PROVIDER: S-EPMC10961850 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature