Anatomical details affect electric field predictions for non-invasive brain stimulation in non-human primates.

ABSTRACT: Non-human primates (NHPs) have become key for translational research in noninvasive brain stimulation (NIBS). However, in order to create comparable stimulation conditions for humans it is vital to study the accuracy of current modeling practices across species. Numerical models to simulate electric fields are an important tool for experimental planning in NHPs and translation to human studies. It is thus essential whether and to what extent the anatomical details of NHP models agree with current modeling practices when calculating NIBS electric fields. Here, we create highly accurate head models of two non-human primates (NHP) MR data. We evaluate how muscle tissue and head field of view (depending on MRI parameters) affect simulation results in transcranial electric and magnetic stimulat

SUBMITTER: Mantell KE 

PROVIDER: S-EPMC10961993 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature