Triglyceride-glucose index in early pregnancy predicts the risk of gestational diabetes: a prospective cohort study.

ABSTRACT:

Objective

This study aimed to investigate the association between the triglyceride-glucose (TyG) index in early pregnancy and the development of gestational diabetes mellitus (GDM) in the second trimester. The primary objectives were to evaluate the predictive potential of the TyG index for GDM, determine the optimal threshold value of the TyG index for GDM assessment, and compare the predictive performance of the TyG index alone versus its combination with maternal age and pre-pregnancy body mass index on GDM. Moreover, the study explored the association between the TyG index in early pregnancy and the risk of other pregnancy-related complications (PRCs), such as placental abruption and gestational hypertension.

Patients and methods

This prospective cohort study recruited 1

SUBMITTER: Guo Y 

PROVIDER: S-EPMC10962154 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature