Tizanidine: Advances in Pharmacology & Therapeutics and Drug Formulations.

ABSTRACT:

Background

Skeletal muscle relaxants (SMRs) are widely used in treating musculoskeletal conditions. All SMRs, with the exception of baclofen and tizanidine, are on the list of 2023 American Geriatrics Society Beers Criteria^® for potentially inappropriate medication use in older adults. In our geriatric practice, off-label use of tizanidine as preemptive analgesia drove us to find recent advances in its pharmacology and therapeutics. An update review of tizanidine was thus presented, aiming to bring the latest knowledge to clinicians and promote further research and practical exploration.

Methods

Relevant literature up to December 2023 was identified through searches of PubMed, Web of Science, and Embase.

Results

Tizanidine, a centrally acting alpha-2 adreno

SUBMITTER: Zhu LL 

PROVIDER: S-EPMC10962466 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature