Temporal stability of intracranial electroencephalographic abnormality maps for localizing epileptogenic tissue.

ABSTRACT:

Objective

Identifying abnormalities on interictal intracranial electroencephalogram (iEEG), by comparing patient data to a normative map, has shown promise for the localization of epileptogenic tissue and prediction of outcome. The approach typically uses short interictal segments of approximately 1 min. However, the temporal stability of findings has not been established.

Methods

Here, we generated a normative map of iEEG in nonpathological brain tissue from 249 patients. We computed regional band power abnormalities in a separate cohort of 39 patients for the duration of their monitoring period (.92-8.62 days of iEEG data, mean = 4.58 days per patient, >4800 hours recording). To assess the localizing value of band power abnormality, we computed DRS -a measure of how differ

SUBMITTER: Wang Y 

PROVIDER: S-EPMC10962550 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature