Therapeutic effects of orally administration of viable and inactivated probiotic strains against murine urinary tract infection.

ABSTRACT: Urinary tract infections (UTIs) are highly prevalent bacterial infections that pose significant health risks. Specific probiotic strains have been recommended for UTI control and management of antibiotic resistance. Otherwise, para-probiotics, defined as inactivated probiotic cells, offer potential advantages by minimizing risks associated with live microorganisms. However, the effectiveness of heat-killed probiotic strains against UTIs remains uncertain. Additionally, lactoferrin (LF), an iron-binding glycoprotein, exhibits immunomodulatory, antimicrobial, and anti-inflammatory properties. Recently, we had developed recombinant LF-expression probiotics, which can display considerate antibacterial activities against select food-borne pathogens in vitro. Thus, the present study aimed to eva

SUBMITTER: Van VTH 

PROVIDER: S-EPMC10962665 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature