Establishment of reference interval for hemoglobin A1C and other hemoglobin subfractions for healthy Saudi adults.

ABSTRACT:

Background

The establishment of Reference Intervals (RIs) for Hemoglobin A1C and other hemoglobin subfractions (A1A, A1B, F, LA1C, A0) is of utmost importance in screening, diagnosing, and monitoring diabetes and other hemoglobin abnormalities through the application of high-pressure liquid chromatography (HPLC) technique. Because there are no locally established RIs for these parameters, it is essential to establish RIs specific to the Saudi population to accurately diagnose and monitor diabetic individuals and identify abnormal levels in hemoglobin subfractions.

Methods

As part of the IFCC global multicenter study of laboratory reference values, a cross-sectional study was conducted in Saudi Arabia. The study involved recruiting a total of 381 healthy adult subjects (>18 y

SUBMITTER: Borai A 

PROVIDER: S-EPMC10962850 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature