Frailty Changes After Liver Transplantation. Results From a Spanish Multicenter Prospective Cohort Study.

ABSTRACT:

Introduction

Until now, there has been limited evidence, primarily from US cohorts, focusing on frailty as a patient-oriented outcome after liver transplantation (LT). Our study aimed to explore the relationship between pre- and post-LT frailty in a multicenter European cohort of outpatients with cirrhosis undergoing LT.

Methods

We conducted a prospective analysis of data from 180 LT recipients recruited between 2018 and 2020 from 5 Spanish centers. Participants underwent objective and subjective frailty assessments using the Liver Frailty Index (LFI) and the Subjective Clinician Assessment (SCA) pretransplant and at 3- and/or 6-mo posttransplant.

Results

The median pretransplant LFI was 3.9, showing minimal change at 3 mo (3.8; P = 0.331) and improvement at 6-

SUBMITTER: Puchades L 

PROVIDER: S-EPMC10962876 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature