Types of diabetes during pregnancy and risk of depression and anxiety in offspring from childhood to young adulthood.

ABSTRACT:

Aims

To assess maternal pre-existing type 1 diabetes (T1D), type 2 diabetes (T2D), gestational diabetes mellitus (GDM) during pregnancy and risk of depression and anxiety from childhood to young adulthood in offspring.

Materials and methods

This birth cohort included singletons born during 1995-2015, followed using electronic medical records through 2020. Cox regression was used to estimate hazard ratio (HR) of depression or anxiety diagnosis during follow-up associated with in-utero exposure to maternal diabetes.

Results

Among 439 590 offspring, 29 891 (6.8%) had depression and 51 918 (11.8%) had anxiety. T1D, followed by T2D and GDM requiring antidiabetes medication were associated with risk of depression and anxiety in offspring. Compared with no diabetes during pr

SUBMITTER: Xiang AH 

PROVIDER: S-EPMC10962903 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature