Global sensitivity of EEG source analysis to tissue conductivity uncertainties.

ABSTRACT:

Introduction

To reliably solve the EEG inverse problem, accurate EEG forward solutions based on a detailed, individual volume conductor model of the head are essential. A crucial-but often neglected-aspect in generating a volume conductor model is the choice of the tissue conductivities, as these may vary from subject to subject. In this study, we investigate the sensitivity of EEG forward and inverse solutions to tissue conductivity uncertainties for sources distributed over the whole cortex surface.

Methods

We employ a detailed five-compartment head model distinguishing skin, skull, cerebrospinal fluid, gray matter, and white matter, where we consider uncertainties of skin, skull, gray matter, and white matter conductivities. We use the finite element method (FEM) to calcu

SUBMITTER: Vorwerk J 

PROVIDER: S-EPMC10963400 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature