Potential of computational models in personalized treatment of obstructive sleep apnea: a patient-specific partial 3D finite element study.

ABSTRACT: The upper airway experiences mechanical loads during breathing. Obstructive sleep apnea is a very common sleep disorder, in which the normal function of the airway is compromised, enabling its collapse. Its treatment remains unsatisfactory with variable efficacy in the case of many surgeries. Finite element models of the upper airway to simulate the effects of various anatomic and physiologic manipulations on its mechanics could be helpful in predicting surgical success. Partial 3D finite element models based on patient-specific CT-scans were undertaken in a pilot study of 5 OSA patients. Upper airway soft tissues including the soft palate, hard palate, tongue, and pharyngeal wall were segmented around the midsagittal plane up to a width of 2.5 cm in the lateral direction. Simulations of s

SUBMITTER: Ayyalasomayajula V 

PROVIDER: S-EPMC10963546 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature