Pharmacological Treatment of Alcohol use Disorder in Patients with Psychotic Disorders: A Systematic Review.

ABSTRACT:

Background

Patients with psychotic disorders (PD) often have comorbid alcohol use disorder (AUD), which is typically treated pharmacologically. Up till now, no systematic review has examined the effectiveness and safety of AUD treatment in PD patients.

Objectives

This study aimed to systematically review the literature on (1) the effects of pharmacological treatments for AUD on drinking outcomes, (2) the side effects of the drugs, and (3) the effects of polypharmacy in patients with comorbid AUD and PD.

Methods

Bibliographic searches were conducted in MEDLINE, Embase, Cochrane Central Register of Controlled Trials, and PsycINFO. At least two reviewers extracted the data, assessed the risk of bias, and performed the qualitative synthesis of the collected evidence.

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SUBMITTER: Rosenstand NJ 

PROVIDER: S-EPMC10964102 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature