The impact of age, disease severity, and BMI on bone health and growth in children and young people with Crohn's disease.

ABSTRACT:

Objectives

The objective of this study was to explore the correlation between paediatric Crohn's disease (CD) characteristics, bone health and growth parameters at diagnosis and follow-up.

Methods

Retrospective data was collected for 47 children aged 4-16 who were newly diagnosed with CD between January 2018 and December 2019. Mean follow-up time was 2.5 years.

Results

Eleven (24%) children had growth delay at diagnosis, which persisted in 4 (44%) of 9 recorded children at follow-up. Of the 35 children tested, 20 (57%) had inadequate Vitamin D levels (<50 mmol/L) at diagnosis. Thirty-seven (79%) children had a dual-energy X-ray absorptiometry scan at diagnosis, with 20 of them having at least 1 low Z-score. Children with poorer bone mineral density and bone min

SUBMITTER: Kherati R 

PROVIDER: S-EPMC10964338 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature