Association between genetic risk and adherence to healthy lifestyle for developing age-related hearing loss.

ABSTRACT:

Background

Previous studies have shown that lifestyle/environmental factors could accelerate the development of age-related hearing loss (ARHL). However, there has not yet been a study investigating the joint association among genetics, lifestyle/environmental factors, and adherence to healthy lifestyle for risk of ARHL. We aimed to assess the association between ARHL genetic variants, lifestyle/environmental factors, and adherence to healthy lifestyle as pertains to risk of ARHL.

Methods

This case-control study included 376,464 European individuals aged 40 to 69 years, enrolled between 2006 and 2010 in the UK Biobank (UKBB). As a replication set, we also included a total of 26,523 individuals considered of European ancestry and 9834 individuals considered of African-America

SUBMITTER: Jung SH 

PROVIDER: S-EPMC10964689 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature