Interventions to Optimize Spinal Cord Perfusion in Patients With Acute Traumatic Spinal Cord Injury: An Updated Systematic Review.

ABSTRACT:

Study design

Systematic review update.

Objectives

Interventions that aim to optimize spinal cord perfusion are thought to play an important role in minimizing secondary ischemic damage and improving outcomes in patients with acute traumatic spinal cord injuries (SCIs). However, exactly how to optimize spinal cord perfusion and enhance neurologic recovery remains controversial. We performed an update of a recent systematic review (Evaniew et al, J. Neurotrauma 2020) to evaluate the effects of Mean Arterial Pressure (MAP) support or Spinal Cord Perfusion Pressure (SCPP) support on neurological recovery and rates of adverse events among patients with acute traumatic SCI.

Methods

We searched PubMed/MEDLINE, EMBASE and ClinicalTrials.gov for new published reports. Two revi

SUBMITTER: Evaniew N 

PROVIDER: S-EPMC10964891 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature