Dysregulation of LINC00324 promotes poor prognosis in patients with glioma.

ABSTRACT:

Background

LINC00324 is a long-stranded non-coding RNA, which is aberrantly expressed in various cancers and is associated with poor prognosis and clinical features. It involves multiple oncogenic molecular pathways affecting cell proliferation, migration, invasion, and apoptosis. However, the expression, function, and mechanism of LINC00324 in glioma have not been reported.

Material and methods

We assessed the expression of LINC00324 of LINC00324 in glioma patients based on data from The Cancer Genome Atlas (TCGA) and Genotype-Tissue Expression (GTEx) to identify pathways involved in LINC00324-related glioma pathogenesis.

Results

Based on our findings, we observed differential expression of LINC00324 between tumor and normal tissues in glioma patients. Our analysis o

SUBMITTER: Jin X 

PROVIDER: S-EPMC10965094 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature