Body weight variation is not an independent factor in the determination of functional hypothalamic amenorrhea in anorexia nervosa.

ABSTRACT:

Objective

Functional hypothalamic amenorrhea (FHA) is one of the foremost manifestations in anorexia nervosa (AN), but a subset of patients have menses despite marked weight loss and underweight. The aim of our study was to investigate parameters potentially influencing FHA in AN.

Design and methods

In this observational retrospective study, we selected 114 female patients with AN who completed a 12 months semi-residential rehabilitation program and a subsequent 12 months outpatient follow-up. We divided our sample into three groups: "Group 0" patients who experienced FHA and recovered their menses, "Group 1" persistent FHA, "Group 2" never experienced FHA, and looked for clinical and hormonal correlations.

Results

At the enrollment, the BMI was higher in Group 2 than

SUBMITTER: Cacciatore C 

PROVIDER: S-EPMC10965633 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature