Patient-reported outcomes in Hodgkin lymphoma trials: a systematic review.

ABSTRACT:

Background

Lymphoma treatment can lead to long-term consequences such as fatigue, infertility and organ damage. In clinical trials, survival outcomes, clinical response and toxicity are extensively reported while the assessment of treatment on quality of life (QoL) and symptoms is often lacking.

Objective

We evaluated the use and frequency of patient-reported outcome (PRO) instruments used in randomized controlled trials (RCTs) for Hodgkin lymphoma (HL) and their consistency of reporting.

Methods

MEDLINE, CENTRAL and trial registries for RCTs investigating HL were systematically searched from 01/01/2016 to 31/05/2022. Following trial selection, trial, patient characteristics and outcome data on the use of PRO measures (PROMs) and reporting of PROs using a pre-defined

SUBMITTER: Oliva EN 

PROVIDER: S-EPMC10965683 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature