4CMenB Vaccination to Prevent Meningococcal B Disease in Vietnam: Expert Review and Opinion.

ABSTRACT: An advisory board meeting was held with experts in Vietnam (Hanoi, August 2022), to review the evidence on invasive meningococcal disease (IMD) epidemiology, clinical management, and meningococcal vaccines to reach a consensus on recommendations for meningococcal vaccination in Vietnam. IMD is a severe disease, with the highest burden in infants and children. IMD presents as meningitis and/or meningococcemia and can progress extremely rapidly. Almost 90% of deaths in children occur within the first 24 h, and disabling sequelae (e.g., limb amputations and neurological damage) occur in up to 20% of survivors. IMD patients are often hospitalized late, due to mild and nonspecific early symptoms and misdiagnosis. Difficulties related to diagnosis and antibiotic misuse mean that the number of re

SUBMITTER: Nguyen PNT 

PROVIDER: S-EPMC10965853 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature