Accuracy of Diagnosing Heparin-Induced Thrombocytopenia.

ABSTRACT:

Importance

Heparin-induced thrombocytopenia (HIT) is a life-threatening condition that requires urgent diagnostic clarification. However, knowledge of the diagnostic utility of the recommended diagnostic tests is limited in clinical practice.

Objective

To evaluate the current diagnostic practice for managing the suspicion of HIT.

Design, setting, and participants

This prospective diagnostic study was conducted from January 2018 to May 2021 among consecutive patients with suspected HIT from 11 study centers in Switzerland, Germany, and the United States. Detailed clinical data and laboratory information were recorded. Platelet factor 4/heparin antibodies were quantified using an automated chemiluminescent immunoassay (CLIA). A washed-platelet heparin-induced platelet a

SUBMITTER: Larsen EL 

PROVIDER: S-EPMC10966416 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature