Atypical co-development of the thalamus and cortex in autism: Evidence from age-related white-gray contrast change.

ABSTRACT: Recent studies have shown that white-gray contrast (WGC) of either cortical or subcortical gray matter provides for accurate predictions of age in typically developing (TD) children, and that, at least for the cortex, it changes differently with age in subjects with autism spectrum disorder (ASD) compared to their TD peers. Our previous study showed different patterns of contrast change between ASD and TD in sensorimotor and association cortices. While that study was confined to the cortex, we hypothesized that subcortical structures, particularly the thalamus, were involved in the observed cortical dichotomy between lower and higher processing. The current paper investigates that hypothesis using the WGC measures from the thalamus in addition to those from the cortex. We compared age-rela

SUBMITTER: Bezgin G 

PROVIDER: S-EPMC10966578 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature