Association between osteoarthritis and cardiovascular disease in elderly in Japan: an administrative claims database analysis.

ABSTRACT:

Objective

To investigate whether osteoarthritis (OA) is a risk factor for cardiovascular disease (CVD); whether there are differences concerning ischaemic heart disease (IHD), congestive heart failure (CHF) and stroke; and whether there are differences between OA sites (hips, knees and hand) in predicting CVD onset.

Design

Population-based matched case-control study.

Setting

Health insurance claims data among Japanese patients.

Participants

Japanese patients aged ≥65 years with newly diagnosed CVD and hospitalised between January 2015 and December 2020 (cases) and age-matched and sex-matched 1:1 individuals (controls).

Main outcome measures

A conditional logistic regression model was used to estimate the adjusted ORs and their 95% CIs for CVD, IHD, CHF a

SUBMITTER: Uematsu T 

PROVIDER: S-EPMC10966792 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature