Associations of prior pulmonary tuberculosis with the incident COPD: a prospective cohort study.

ABSTRACT:

Background

Prior pulmonary tuberculosis (PTB) might be associated with the development of chronic obstructive pulmonary disease (COPD). However, the impact of prior PTB on the risk of incident COPD has not been studied in a large prospective cohort study of the European population.

Objectives

This study aimed to investigate the association of prior PTB with the risk of COPD.

Design

Prospective cohort study.

Methods

A multivariable Cox proportional model was used to estimate the hazard ratio (HR) and 95% confidence interval (95% CI) for the association of prior PTB with COPD. Subgroup analyses were further conducted among individuals stratified by age, sex, body mass index, smoking status, drinking status, physical activity, and polygenic risk score (PRS).

Re

SUBMITTER: Zeng Z 

PROVIDER: S-EPMC10966999 | biostudies-literature | 2024 Jan-Dec

REPOSITORIES: biostudies-literature