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Expansion and diversity of caspases in Mytilus coruscus contribute to larval metamorphosis and environmental adaptation.


ABSTRACT:

Background

Apoptosis is involved (directly and indirectly) in several physiological processes including tissue remodeling during the development, the turnover of immune cells, and a defense against harmful stimuli. The disordered apoptotic process participates in the pathogenesis of various diseases, such as neoplasms, and chronic inflammatory or systemic autoimmune diseases, which are associated with its inadequate regulation. Caspases are vital components of the apoptotic pathway that are involved in developmental and immune processes. However, genome-wide identification and functional analysis of caspase have not been conducted in Mytilus coruscus, which is an economically important bivalve.

Results

Here, 47 caspase genes were identified from the genomes of M. coruscus, a

SUBMITTER: Cao Y 

PROVIDER: S-EPMC10967218 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature