Real-World Effectiveness of Mepolizumab in Patients with Allergic and Non-Allergic Asthma.

ABSTRACT:

Purpose

Real-world data on mepolizumab in patients with severe asthma and allergic and non-allergic phenotypes are limited. This study investigated the effectiveness of mepolizumab treatment in patients with severe asthma with allergic and non-allergic phenotypes.

Patients and methods

This retrospective cohort study (GSK ID: 214148) used administrative claims data from the Optum Research Database. Eligible patients were ≥6 years of age with asthma and had ≥2 mepolizumab claims post-index. Index date was the first mepolizumab claim/administration (January 2016-December 2018). Patients were divided into two cohorts: allergic and non-allergic asthma, based on diagnosis codes, medication use and lab test results. Outcomes included the rate of asthma-related exacerbations and ora

SUBMITTER: Silver J 

PROVIDER: S-EPMC10967551 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature