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CD44 in Bladder Cancer.

ABSTRACT: The glycoprotein CD44, with its many isoforms and variations in carbohydrate patterning, participates in a diverse set of cellular functions. This fact leads to the protein playing a role in many normal and pathologic cellular processes including a role in cancer progression and metastasis. These same facts make CD44 a strong therapeutic target in many cancer types, including bladder cancer.

SUBMITTER: Duex J 

PROVIDER: S-EPMC10969618 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature

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CD44 in Bladder Cancer.

Duex Jason J   Theodorescu Dan D  

Cancers 20240318 6

The glycoprotein CD44, with its many isoforms and variations in carbohydrate patterning, participates in a diverse set of cellular functions. This fact leads to the protein playing a role in many normal and pathologic cellular processes including a role in cancer progression and metastasis. These same facts make CD44 a strong therapeutic target in many cancer types, including bladder cancer. ...[more]

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