Raman Spectroscopy as a Research and Diagnostic Tool in Clinical Hematology and Hematooncology.

ABSTRACT: Raman spectroscopy is a molecular spectroscopic technique able to provide detailed information about the chemical structure, phase, crystallinity, and molecular interactions of virtually any analyzed sample. Although its medical applications have been studied for several decades, only recent advances in microscopy, lasers, detectors, and better understanding of the principles of the Raman effect have successfully expanded its applicability to clinical settings. The promise of a rapid, label-free diagnostic method able to evaluate the metabolic status of a cell in vivo makes Raman spectroscopy particularly attractive for hematology and oncology. Here, we review widely studied hematological applications of Raman spectroscopy such as leukocyte activation status, evaluation of treatment respon

SUBMITTER: Laskowska P 

PROVIDER: S-EPMC10969935 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature