Exploring the miRNAs Profile in Dark-Cutting Beef.

ABSTRACT: In an animal production system, different stressors may cause the depletion of muscle glycogen stores, resulting in an elevated pH at 24 h post mortem (pH₂₄), which leads to cell metabolism alterations that affect the conversion of muscle into meat, causing meat quality defects, such as dark-cutting beef, also known as dark, firm, and dry (DFD) beef. This process may involve the alteration of small non-coding RNAs (miRNAs), which play critical regulatory roles in cellular processes. Here, we determined whether differential miRNA expression in the Longissimus thoracis et lumborum muscle from the Asturiana de los Valles breed at 24 h post mortem could serve as an early indicator of beef quality defects. Following total RNA extraction, complete miRNAome sequenc

SUBMITTER: Gonzalez-Blanco L 

PROVIDER: S-EPMC10970431 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature