The Omics Complexity in Sepsis: The Limits of the Personalized Medicine Approach.

ABSTRACT: Sepsis is one of the most common causes of morbidity and mortality worldwide. Despite the remarkable advances in modern medicine throughout the last century, the mortality rates associated with sepsis have remained significantly elevated, both in high- and low-income countries. The main difficulty in the diagnosis and treatment of septic patients is the tremendous heterogeneity of this condition. The vast heterogeneity that characterizes sepsis ranges from the clinical presentation to the biological aspects of the disease. Evidence-based medicine approaches sepsis as a homogenous syndrome and does not consider the individual discrepancies between septic patients. This approach may contribute to the poor outcomes of septic patients. In recent years, personalized medicine has gained signific

SUBMITTER: Isac S 

PROVIDER: S-EPMC10971110 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature