Histone Acetylation Enhancing Host Melanization in Response to Parasitism by an Endoparasitoid Wasp.

ABSTRACT: Endoparasitoids are insects that develop within other insects, employing unique strategies to enhance their offspring's survival. They inject polydnavirus and/or venom into their hosts along with eggs, effectively suppressing the host's immune system. Polydnavirus from Braconidae and Ichneumonidae wasps can integrate into the host's genome to express viral genes using the host's transcription systems. However, the ability of parasitoids without polydnavirus to manipulate host gene expression remains unclear. Lysine acetylation (LysAc), a post-translational modification critical for gene regulation, is hypothesized to be used by endoparasitoids lacking polydnavirus. We utilized the Chalcidoidea wasp Tetrastichus brontispae, which lacks polydnavirus, as an idiobiont endoparasitoid mod

SUBMITTER: Jiang K 

PROVIDER: S-EPMC10971516 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature