Iron Oxide (Magnetite)-Based Nanobiomaterial with Medical Applications-Environmental Hazard Assessment Using Terrestrial Model Species.

ABSTRACT: Nanobiomaterials (NBMs) have tremendous potential applications including in cancer diagnosis and treatment. However, the health and environmental effects of NBMs must be thoroughly assessed to ensure safety. Fe₃O₄ (magnetite) nanoparticles coated with polyethylene glycol (PEG) and poly (lactic-co-glycolic acid) (PLGA) were one of the focus NBMs within the EU project BIORIMA. Fe₃O₄ PEG-PLGA has been proposed to be used as a contrast agent in magnetic resonance imaging for the identification of solid tumors and has revealed low cytotoxicity in several cell lines. However, the effects of Fe₃O₄ PEG-PLGA have not been assessed in terrestrial environments, the eventual final sink of most materials. In the present study, the effect

SUBMITTER: Gomes SIL 

PROVIDER: S-EPMC10971733 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature