Natural Products Derived from Marine Sponges with Antitumor Potential against Lung Cancer: A Systematic Review.

ABSTRACT: Non-small-cell lung cancer (NSCLC), the most commonly diagnosed cancer and the leading cause of cancer-related death worldwide, has been extensively investigated in the last decade in terms of developing new therapeutic options that increase patient survival. In this context, marine animals are a source of new, interesting bioactive molecules that have been applied to the treatment of different types of cancer. Many efforts have been made to search for new therapeutic strategies to improve the prognosis of lung cancer patients, including new bioactive compounds and cytotoxic drugs from marine sponges. Their antitumoral effect can be explained by several cellular and molecular mechanisms, such as modulation of the cell cycle or induction of apoptosis. Thus, this systematic review aims to su

SUBMITTER: Ortigosa-Palomo A 

PROVIDER: S-EPMC10971797 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature