Effectiveness of sigmoidoscopy or colonoscopy screening on colorectal cancer incidence and mortality: a systematic review and meta-analysis of randomized controlled trial.

ABSTRACT:

Objectives

We conducted a comprehensive analysis to compare colonoscopy and sigmoidoscopy with standard care or fecal immunochemistry regarding colorectal cancer incidence and mortality risk.

Methods

Until August 2023, literature from PubMed, Embase, Web of Science, and Cochrane was systematically reviewed. We examined the impact of colonoscopy or sigmoidoscopy versus standard care on colorectal cancer outcomes, including incidence, cancer-specific mortality, and overall mortality.

Results

Among 4,265 screened articles, data from seven randomized controlled trials (involving 663,319 participants) were analyzed. The intervention group (colonoscopy or sigmoidoscopy) consisted of 258,938 participants, while the control group received standard care or fecal immunochemical

SUBMITTER: Han C 

PROVIDER: S-EPMC10972922 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature