Exploring brain network oscillations during seizures in drug-naive patients with juvenile absence epilepsy.

ABSTRACT:

Objective

We aimed to investigate the brain network activity during seizures in patients with untreated juvenile absence epilepsy.

Methods

Thirty-six juvenile absence epilepsy (JAE) patients with a current high frequency of seizures (more than five seizures during a 2 h EEG examination) were included. Each participant underwent a 2 h video EEG examination. Five 10 s EEG epochs for inter-ictal, pre-ictal, and post-ictal, and five 5 s EEG epochs for ictal states were extracted. Five 10 s resting-state EEG epochs for each participant from a sex- and age-matched healthy control (HC) were enrolled. The topological parameters of the brain networks were calculated using a graph theory analysis.

Results

Compared with the resting state of the HC group, the global efficiency, l

SUBMITTER: Tan L 

PROVIDER: S-EPMC10972980 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature