NT-proBNP detection with a one-step magnetic lateral flow channel assay.

ABSTRACT: Point-of-care sensors targeting blood marker analysis must be designed to function with very small volumes since acquiring a blood sample through a simple, mostly pain-free finger prick dramatically limits the sample size and comforts the patient. Therefore, we explored the potential of converting a conventional lateral flow assay (LFA) for a significant biomarker into a self-contained and compact polymer channel-based LFA to minimize the sample volume while maintaining the analytical merits. Our primary objective was to eliminate the use of sample-absorbing fleece and membrane materials commonly present in LFAs. Simultaneously, we concentrated on developing a ready-to-deploy one-step LFA format, characterized by dried reagents, facilitating automation and precise sample transport through

SUBMITTER: Strohmaier-Nguyen D 

PROVIDER: S-EPMC10973066 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature