Lack of association between COVID-19 vaccines and miscarriage onset using a case-crossover design.

ABSTRACT: Pregnant women might have an increased risk of SARS-COV-2 infection. Although evidence towards the efficacy and safety of COVID-19 is growing still there is room for improvement on the knowledge towards pregnancy adverse events, such as miscarriage. We explored the association of COVID-19 vaccine with the risk of miscarriages using the Real-World. We identified a cohort of vaccinated pregnancies using the BIFAP database which contains systematically recorded data on care patients in Spain (N = 4054). We then restricted it to those women who had a miscarriage using a validated algorithm (N = 607). Among them, we performed a case-crossover design to evaluate the effect of intermittent exposures on the risk of miscarriage. Adjusted Odds Ratio with their confidence intervals were calculated us

SUBMITTER: Gastesi Orbegozo I 

PROVIDER: S-EPMC10973422 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature