Interpretation of Complete Tumor Response on MRI Following Chemoradiotherapy of Rectal Cancer: Inter-Reader Agreement and Associated Factors in Multi-Center Clinical Practice.

ABSTRACT:

Objective

To measure inter-reader agreement and identify associated factors in interpreting complete response (CR) on magnetic resonance imaging (MRI) following chemoradiotherapy (CRT) for rectal cancer.

Materials and methods

This retrospective study involved 10 readers from seven hospitals with experience of 80-10210 cases, and 149 patients who underwent surgery after CRT for rectal cancer. Using MRI-based tumor regression grading (mrTRG) and methods employed in daily practice, the readers independently assessed mrTRG, CR on T2-weighted images (T2WI) denoted as mrCR_T2W, and CR on all images including diffusion-weighted images (DWI) denoted as mrCR_overall. The readers described their interpretation patterns and how they utilized DWI. Inter-reader agreem

SUBMITTER: Kim HY 

PROVIDER: S-EPMC10973736 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature