Continuous Glucose Profiles in Healthy People With Fixed Meal Times and Under Everyday Life Conditions.

ABSTRACT:

Background

The increased use of continuous glucose monitoring (CGM) and automated insulin delivery systems raises the question about therapeutic targets for glucose profiles in people with diabetes. This study aimed to assess averaged pre- and postprandial glucose profiles in people without diabetes to provide guidance for normal glucose patterns in clinical practice. For that, number and timing of meal intake were predefined.

Material and methods

To assess glucose traces in 36 participants without diabetes (mean age = 23.7 ± 5.7 years), CGM was performed for up to 14 days, starting with a run-in phase (first 3 days, excluded from analysis) followed by 4 days with fixed meal times at 8:00 am, 1:00 pm, and 6:00 pm and the remaining 7 days spent under everyday life conditions.

SUBMITTER: Freckmann G 

PROVIDER: S-EPMC10973852 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature