Feline Chronic Gingivostomatitis Diagnosis and Treatment through Transcriptomic Insights.

ABSTRACT: Feline chronic gingivostomatitis (FCGS) is a debilitating inflammatory oral mucosal disease with a multifactorial etiology. The clinical diagnosis of FCGS is made based on inspection of severe inflammatory lesions and histological confirmation rather than a molecular diagnostic outcome. This gap limits the ability to provide an early diagnosis. In this report, we seek to provide additional diagnostic tools using genomics to aid in providing clinically relevant information. The use of in-depth diagnostic tools, like transcriptomics of diseased tissues, to diagnose FCGS and stratify patients into predictive treatment response groups would dramatically improve both clinical decisions and patient outcomes. In this study, we addressed the gap in diagnostic options using transcriptomic analysis

SUBMITTER: Soltero-Rivera M 

PROVIDER: S-EPMC10974286 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature