Confinement Effect in Metal-Organic Framework Cu₃(BTC)₂ for Enhancing Shape Selectivity of Radical Difunctionalization of Alkenes.

ABSTRACT: The radical difunctionalization of alkenes plays a vital role in pharmacy, but the conventional homogeneous catalytic systems are challenging in selectivity and sustainability to afford the target molecules. Herein, the famous readily available metal-organic framework (MOF), Cu₃(BTC)₂, has been applied to cyano-trifluoromethylation of alkenes as a high-performance and recyclable heterogeneous catalyst, which possesses copper(II) active sites residing in funnel-like cavities. Under mild conditions, styrene derivatives and various unactivated olefins could be smoothly transformed into the corresponding cyano-trifluoromethylation products. Moreover, the transformation brought about by the active copper center in confined environments achieved regio- and shape sele

SUBMITTER: Li M 

PROVIDER: S-EPMC10976352 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature