Burden of Disease of Duchenne Muscular Dystrophy in Denmark - A National Register-Based Study of Individuals with Duchenne Muscular Dystrophy and their Closest Relatives.

ABSTRACT:

Background

Duchenne Muscular Dystrophy (DMD) is a progressive genetic disease with a prevalence of 1 per 3,600-6,000 male births. Individuals with DMD are typically diagnosed at age 4-7 years; median survival is 30 years. They require multidisciplinary care, personal assistance, and often special education.

Objective

The aim was to assess the burden of disease in DMD in Denmark. This includes incidence, prevalence, use of healthcare services, labour market participation, educational outcomes, and overall attributable costs due to DMD. Impact on the closest relatives (siblings and parents) was also investigated.

Methods

The comprehensive Danish national health and administrative registers were used to assess the burden of disease following individuals with DMD and clos

SUBMITTER: Rudolfsen JH 

PROVIDER: S-EPMC10977402 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature