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Serial Bronchoalveolar Lavage Fluid Aspergillus Galactomannan and Treatment Response in Invasive Pulmonary Aspergillosis.

ABSTRACT: We studied patients diagnosed with aspergillosis based on positive bronchoalveolar lavage (BAL) Aspergillus galactomannan (GM) who had follow-up BAL sampling within 180 days. GM trend and clinical outcome were concordant in only 60% (30/50). While useful for the initial diagnosis, BAL GM trending does not always correlate with treatment response.

SUBMITTER: Friedman DZP 

PROVIDER: S-EPMC10977621 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature

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Serial Bronchoalveolar Lavage Fluid <i>Aspergillus</i> Galactomannan and Treatment Response in Invasive Pulmonary Aspergillosis.

Friedman Daniel Z P DZP   Theel Elitza S ES   Walker Randall C RC   Vikram Holenarasipur R HR   Razonable Raymund R RR   Vergidis Paschalis P  

Open forum infectious diseases 20240301 4

We studied patients diagnosed with aspergillosis based on positive bronchoalveolar lavage (BAL) <i>Aspergillus</i> galactomannan (GM) who had follow-up BAL sampling within 180 days. GM trend and clinical outcome were concordant in only 60% (30/50). While useful for the initial diagnosis, BAL GM trending does not always correlate with treatment response. ...[more]

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