National clinical and financial outcomes associated with acute kidney injury following esophagectomy for cancer.

ABSTRACT:

Background

Esophagectomy is a complex oncologic operation associated with high rates of postoperative complications. While respiratory and septic complications have been well-defined, the implications of acute kidney injury (AKI) remain unclear. Using a nationally representative database, we aimed to characterize the association of AKI with mortality, resource use, and 30-day readmission.

Methods

All adults undergoing elective esophagectomy with a diagnosis of esophageal or gastric cancer were identified in the 2010-2019 Nationwide Readmissions Database. Study cohorts were stratified based on presence of AKI. Multivariable regressions and Royston-Parmar survival analysis were used to evaluate the independent association between AKI and outcomes of interest.

Results

Of

SUBMITTER: Ng AP 

PROVIDER: S-EPMC10977786 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature