Deaths Associated with Pediatric Hepatitis of Unknown Etiology, United States, October 2021-June 2023.

ABSTRACT: During October 2021-June 2023, a total of 392 cases of acute hepatitis of unknown etiology in children in the United States were reported to Centers for Disease Control and Prevention as part of national surveillance. We describe demographic and clinical characteristics, including potential involvement of adenovirus in development of acute hepatitis, of 8 fatally ill children who met reporting criteria. The children had diverse courses of illness. Two children were immunocompromised when initially brought for care. Four children tested positive for adenovirus in multiple specimen types, including 2 for whom typing was completed. One adenovirus-positive child had no known underlying conditions, supporting a potential relationship between adenovirus and acute hepatitis in previously healthy

SUBMITTER: Almendares O 

PROVIDER: S-EPMC10977843 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature