GC Content Across Insect Genomes: Phylogenetic Patterns, Causes and Consequences.

ABSTRACT: The proportions of A:T and G:C nucleotide pairs are often unequal and can vary greatly between animal species and along chromosomes. The causes and consequences of this variation are incompletely understood. The recent release of high-quality genome sequences from the Darwin Tree of Life and other large-scale genome projects provides an opportunity for GC heterogeneity to be compared across a large number of insect species. Here we analyse GC content along chromosomes, and within protein-coding genes and codons, of 150 insect species from four holometabolous orders: Coleoptera, Diptera, Hymenoptera, and Lepidoptera. We find that protein-coding sequences have higher GC content than the genome average, and that Lepidoptera generally have higher GC content than the other three insect orders e

SUBMITTER: Kyriacou RG 

PROVIDER: S-EPMC10978632 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature