Prescribing cascades of antigout medications from thiazide diuretics in gout-naive hypertensive adults receiving first-line pharmacological management.

ABSTRACT: Prescribing cascade is a significant clinical problem but is often overlooked. We explore the incidence of the prescribing cascades of antigout medications related to thiazide treatment in gout-naïve hypertensive adults newly exposed to the pharmacological treatment. This population-based, retrospective cohort study used the Taiwan National Health Insurance Registry Database. Gout-naïve hypertensive adults who were newly dispensed first-line antihypertensive drugs between January 1, 2000, and December 31, 2016, were enrolled. Patients were divided into the thiazide group (n = 4192) and the non-thiazide group (n = 81,083). The non-thiazide group included patients who received an angiotensin-converting enzyme inhibitor, angiotensin II receptor blocker, calcium channel blocker, or beta-blocke

SUBMITTER: Lu SY 

PROVIDER: S-EPMC10978838 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature