Dataset Information
Enhanced articular cartilage regeneration using costal chondrocyte-derived scaffold-free tissue engineered constructs with ascorbic acid treatment.
Ontology highlight
ABSTRACT:
SUBMITTER: Zheng K
PROVIDER: S-EPMC10979122 | biostudies-literature | 2024 Mar
REPOSITORIES: biostudies-literature
Publications
Enhanced articular cartilage regeneration using costal chondrocyte-derived scaffold-free tissue engineered constructs with ascorbic acid treatment.
Journal of orthopaedic translation 20240322
<h4>Background</h4>Cartilage tissue engineering faces challenges related to the use of scaffolds and limited seed cells. This study aims to propose a cost-effective and straightforward approach using costal chondrocytes (CCs) as an alternative cell source to overcome these challenges, eliminating the need for special culture equipment or scaffolds.<h4>Methods</h4>CCs were cultured at a high cell density with and without ascorbic acid treatment, serving as the experimental and control groups, res ...[more]