Contralateral acupuncture for migraine without aura: a randomized trial protocol with multimodal MRI.

ABSTRACT:

Introduction

Migraine is a common clinical disorder, ranks as the second most disabling disease worldwide, and often manifests with unilateral onset. Contralateral acupuncture (CAT), as a classical acupuncture method, has been proven to be effective in the treatment of migraine without aura (MWoA). However, its neural mechanisms have not been investigated using multimodal magnetic resonance imaging (MRI).

Methods and analysis

In this multimodal neuroimaging randomized trial, a total of 96 female MWoA participants and 30 female healthy controls (HCs) will be recruited. The 96 female MWoA participants will be randomized into three groups: Group A (CAT group), Group B [ipsilateral acupuncture (IAT) group], and Group C (sham CAT group) in a 1:1:1 allocation ratio. Each group wil

SUBMITTER: Chen Z 

PROVIDER: S-EPMC10979701 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature