The in-silico study of the structural changes in the Arthrobacter globiformis choline oxidase induced by high temperature.

ABSTRACT:

Background

Choline oxidase, a flavoprotein, is an enzyme that catalyzes the reaction which converts choline into glycine betaine. Choline oxidase started its journey way back in 1933. However, the impact of the high temperature on its structure has not been explored despite the long history and availability of its crystal structure. Both choline oxidase and its product, glycine betaine, have enormous applications spanning across multiple industries. Understanding how the 3D structure of the enzyme will change with the temperature change can open new ways to make it more stable and useful for industry.

Process

This research paper presents the in-silico study and analysis of the structural changes of A. globiformis choline oxidase at temperatures from 25 °C to 60 °C. A step-wi

SUBMITTER: Kaushik S 

PROVIDER: S-EPMC10980864 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature